Genomic instability

Gadd45a acts as a modifier locus for lymphoblastic lymphoma

Oncology / Immunology / Stem Cells / Survival Analysis / Leukemia / Apoptosis / Molecular Mechanics / Haematology / Humans / Mice / Female / Animals / Therapy / Male / Phenotype / Clinical Sciences / Genomic instability / Age Factors / Feedback loop / Cell Cycle Proteins / Apoptosis / Molecular Mechanics / Haematology / Humans / Mice / Female / Animals / Therapy / Male / Phenotype / Clinical Sciences / Genomic instability / Age Factors / Feedback loop / Cell Cycle Proteins

Nuclear phosphoinositide 3-kinase beta controls double-strand break DNA repair

DNA replication / DNA damage / DNA repair / Multidisciplinary / Mice / Animals / Cell nucleus / Neoplasms / Genomic instability / Protein isoforms / Cell Cycle Proteins / Animals / Cell nucleus / Neoplasms / Genomic instability / Protein isoforms / Cell Cycle Proteins

Nuclear phosphoinositide 3-kinase controls double-strand break DNA repair

DNA replication / DNA damage / DNA repair / Multidisciplinary / Mice / Animals / Cell nucleus / Neoplasms / Genomic instability / Protein isoforms / Cell Cycle Proteins / Animals / Cell nucleus / Neoplasms / Genomic instability / Protein isoforms / Cell Cycle Proteins

Nuclear phosphoinositide 3-kinase β controls double-strand break DNA repair

DNA replication / DNA damage / DNA repair / Multidisciplinary / Mice / Animals / Cell nucleus / Neoplasms / Genomic instability / Protein isoforms / Cell Cycle Proteins / Animals / Cell nucleus / Neoplasms / Genomic instability / Protein isoforms / Cell Cycle Proteins

Nuclear phosphoinositide 3-kinase β controls double-strand break DNA repair

DNA replication / DNA damage / DNA repair / Multidisciplinary / Mice / Animals / Cell nucleus / Neoplasms / Genomic instability / Protein isoforms / Cell Cycle Proteins / Animals / Cell nucleus / Neoplasms / Genomic instability / Protein isoforms / Cell Cycle Proteins

Tuberculosis vaccine strain Mycobacterium bovis BCG Russia is a natural recA mutant

Evolutionary Biology / Genetics / Microbiology / Russia / Biological Sciences / Phylogeny / Tuberculosis / Humans / Mutation / Genomic instability / Genetic Recombination / Mycobacterium bovis / Nucleotides / BCG vaccine / Molecular Sequence Data / Phylogeny / Tuberculosis / Humans / Mutation / Genomic instability / Genetic Recombination / Mycobacterium bovis / Nucleotides / BCG vaccine / Molecular Sequence Data

Chronic oxidative DNA damage due to DNA repair defects causes chromosomal instability in Saccharomyces cerevisiae

Genetics / Oxidative Stress / DNA damage / DNA repair / Molecular Mechanics / Free Radical / Biological Sciences / High Frequency / Saccharomyces cerevisiae / Molecular and cellular biology / Reactive Oxygen Species / Nucleic acid hybridization / Gene Duplication / Time Factors / Oxidative Damage / Model System / Genetic Instability / Genomic instability / Genetic Recombination / Genome Rearrangement / Chronic Inflammation / Large Scale / Oxidative Dna Damage / Chromosomal Instability / Bacterial Infection / Diploidy / Mutation Rate / Base Excision Repair / Free Radical / Biological Sciences / High Frequency / Saccharomyces cerevisiae / Molecular and cellular biology / Reactive Oxygen Species / Nucleic acid hybridization / Gene Duplication / Time Factors / Oxidative Damage / Model System / Genetic Instability / Genomic instability / Genetic Recombination / Genome Rearrangement / Chronic Inflammation / Large Scale / Oxidative Dna Damage / Chromosomal Instability / Bacterial Infection / Diploidy / Mutation Rate / Base Excision Repair

CELLULAR RESPONSES TO DNA DAMAGE

Engineering / Pharmacology / Environmental Health / Radiation Biology / Cell Cycle / DNA damage / DNA repair / Apoptosis / Signal Transduction / Biological Sciences / DNA / Environmental Sciences / Humans / Mutagenesis / Mutation / Escherichia coli / Animals / Cell Death / Pharmacology and toxicology / Fission yeast / Nucleotide Excision Repair / Public health systems and services research / DNA damage response / UV light / Genomic instability / Cell cycle checkpoints / Veterinary Sciences / Ionizing Radiation / Cell Survival / Mutagens / Base Excision Repair / Biochemistry and cell biology / DNA damage / DNA repair / Apoptosis / Signal Transduction / Biological Sciences / DNA / Environmental Sciences / Humans / Mutagenesis / Mutation / Escherichia coli / Animals / Cell Death / Pharmacology and toxicology / Fission yeast / Nucleotide Excision Repair / Public health systems and services research / DNA damage response / UV light / Genomic instability / Cell cycle checkpoints / Veterinary Sciences / Ionizing Radiation / Cell Survival / Mutagens / Base Excision Repair / Biochemistry and cell biology

Giving OMICS spatiotemporal dimensions using exciting new nanoscopy techniques to assess complex cell responses to radiation damage – PART A (Radiomics)

Genetics / Radiobiology of Ionizing Radiation / Confocal Microscopy / DNA damage / DNA repair / DNA / Humans / Radiobiology / Genome / Chromatin / Cell nucleus / Genomic instability / DNA / Humans / Radiobiology / Genome / Chromatin / Cell nucleus / Genomic instability

RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity

Aging / Mitochondria / DNA damage / Biological Sciences / mtDNA / Mitochondrial DNA / Humans / Mice / Animals / Cell Fractionation / HeLa cells / Genomic instability / Age Factors / RecQ Helicases / Mitochondrial DNA / Humans / Mice / Animals / Cell Fractionation / HeLa cells / Genomic instability / Age Factors / RecQ Helicases

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

DNA damage / Transcription Factors / Multidisciplinary / Nature / Humans / Mice / Animals / Cell Death / Chromatin remodeling / Phosphorylation / Williams- Beuren Syndrome / Nucleosomes / Transcription Factor / Phosphotyrosine / Histones / DNA damage response / Genomic instability / Tyrosine Kinase / Mice / Animals / Cell Death / Chromatin remodeling / Phosphorylation / Williams- Beuren Syndrome / Nucleosomes / Transcription Factor / Phosphotyrosine / Histones / DNA damage response / Genomic instability / Tyrosine Kinase

DNA Damage Response

DNA damage / DNA repair / Signal Transduction / Humans / Animals / Phosphorylation / Chromatin / Histones / Genomic instability / Phosphorylation / Chromatin / Histones / Genomic instability

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

DNA damage / Transcription Factors / Multidisciplinary / Nature / Humans / Mice / Animals / Cell Death / Chromatin remodeling / Phosphorylation / Williams- Beuren Syndrome / Nucleosomes / Transcription Factor / Phosphotyrosine / Histones / DNA damage response / Genomic instability / Tyrosine Kinase / DNA double strand breaks / Mice / Animals / Cell Death / Chromatin remodeling / Phosphorylation / Williams- Beuren Syndrome / Nucleosomes / Transcription Factor / Phosphotyrosine / Histones / DNA damage response / Genomic instability / Tyrosine Kinase / DNA double strand breaks

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